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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VANGL2
All Species:
22.73
Human Site:
S323
Identified Species:
50
UniProt:
Q9ULK5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULK5
NP_065068.1
521
59714
S323
T
N
N
S
T
G
Q
S
R
A
V
I
A
A
A
Chimpanzee
Pan troglodytes
XP_001148705
526
60249
S327
S
N
N
A
T
G
Q
S
R
A
M
I
A
A
A
Rhesus Macaque
Macaca mulatta
XP_001115459
590
67361
S392
T
N
N
S
T
G
Q
S
R
A
V
I
A
A
A
Dog
Lupus familis
XP_857378
525
59954
R327
N
N
A
T
G
Q
S
R
A
M
I
A
A
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZD4
521
59752
S323
T
N
N
S
T
G
Q
S
R
A
V
I
A
A
A
Rat
Rattus norvegicus
NP_001103054
526
60086
A329
N
A
T
G
Q
S
R
A
M
I
A
A
A
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232441
524
59613
A327
N
A
S
G
Q
S
R
A
M
I
A
A
A
A
R
Frog
Xenopus laevis
Q90X64
521
60078
S323
T
N
N
S
T
G
Q
S
R
A
V
I
A
A
A
Zebra Danio
Brachydanio rerio
Q8UVJ6
526
60063
S324
T
N
N
S
T
G
Q
S
R
A
M
I
A
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477177
581
65856
Q382
G
V
S
N
S
Q
Q
Q
S
Q
S
R
A
V
L
Honey Bee
Apis mellifera
XP_623905
572
64968
G368
G
S
V
Q
S
R
G
G
S
G
D
R
S
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.3
88.1
73.7
N.A.
99.4
71.8
N.A.
N.A.
72.5
90.5
76.6
N.A.
43.7
43.1
N.A.
N.A.
Protein Similarity:
100
86.3
88.1
86.6
N.A.
99.6
85.5
N.A.
N.A.
86.8
96.5
86.8
N.A.
61.6
60.3
N.A.
N.A.
P-Site Identity:
100
80
100
26.6
N.A.
100
13.3
N.A.
N.A.
13.3
100
93.3
N.A.
13.3
0
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
100
26.6
N.A.
N.A.
33.3
100
100
N.A.
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
10
0
0
0
19
10
55
19
28
91
82
64
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
19
10
55
10
10
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
19
10
55
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
19
10
19
0
0
0
0
% M
% Asn:
28
64
55
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
19
19
64
10
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
19
10
55
0
0
19
0
0
19
% R
% Ser:
10
10
19
46
19
19
10
55
19
0
10
0
10
0
0
% S
% Thr:
46
0
10
10
55
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
37
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _